EFFECT OF ZINC SUPPLEMENTATION ON ANEMIA AMONG PATIENTS ON REGULAR MAINTENANCE HEMODIALYSIS

ORAHIM D. YOUNAN; SHERZAD K. RASHID; AMER A. MEHE

ORAHIM D. YOUNAN Pharmacist, Directorate General of Health, Kurdistan region, Iraq.
SHERZAD K. RASHID Lecturer, Department of Pharmacology, college of pharmacy, university of Duhok, Duhok, Kurdistan region, Iraq.
AMER A. MEHE Lecturer, Department of clinical pharmacy, college of pharmacy, university of Duhok, Duhok, Kurdistan region, Iraq.

Keywords: zinc, anemia, chronic kidney disease, hemodialysis

Abstract

https://doi.org/10.31386/dmj.2020.4.1.10

Background: Zinc deficiency was reported in patients with chronic kidney disease especially among patients on hemodialysis. The objective was to assess the effect of zinc supplementations on the correction of anemia in those patients.

Patients and Methods: In this study, a total of 105 patients over 18-year old, stable and over 6 months on maintenance hemodialysis were enrolled. Blood samples were collected for biochemical and hematological assessments. The patients with zinc deficiency and anemia of chronic disorder were divided randomly into two groups and completed the study. Group 1 completed their treatment with the addition of zinc to their treatment as food supplementation (elementary zinc 50 mg/day) for 6 weeks and the other without zinc supplementation as a control group. Data collection carried out during the period from 8^th January to 1^st June 2019 at the kidney diseases center in Duhok city–Kurdistan region/Iraq. Serum zinc level and anemia parameters were determined.

Results: The patients in group 1 that received zinc supplementation showed a significant increase in the mean of serum zinc (mean of percentage 43.12 %) and correspondingly the mean of hemoglobin (mean of percentage 13.06 %).

Conclusion: There was a positive relationship between increase zinc level and the correction of anemia.

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