QUALITY OF LIFE IN VITILIGO PATIENTS AND ITS RELATION TO VARIOUS VARIABLES IN DUHOK, KURDISTAN REGION, IRAQ
Background: Background and aim: Studies, mainly in developed countries, have found a negative impact of the disease on the Quality of Life (QoL). This was affected by different socio-economic factors and by clinical aspects of the disease. The aim of the present study is to measure the impact of vitiligo on the QoL among patients and to investigate its relation to socio-demographic and clinical factors, in Duhok, Kurdistan Region, Iraq.
Patients and methods: A cross-sectional hospital-based study was conducted on 143 patients aged 16 years and above diagnosed to have vitiligo by a consultant dermatologist. All available patients to the investigator in the outpatient dermatology unit at a tertiary care hospital were asked to participate. An oral consent was obtained then a short questionnaire was filled for each patient regarding socio-demographic factors and clinical features of the disease. The QoL was estimated by using the Dermatology Life Quality Index (DLQI).
Results: The mean age ±SD was 31.85 ± 10.39 years of which 76 were males, and 67 were females. The mean DLQI score was 6.67 (±4.81SD). Only 13.3% reported no effect of the disease on their QoL while 39.9 %, 16.8%, and 30.1 % of patients reported that the disease has small, moderate and very large negative effect, respectively on their QoL. There were no significant differences between the mean DLQI scores and gender, job, type and duration of the disease and current treatment status. The Qol was significantly more negatively affected among younger patients, those with higher education, married women, patient with darker skin type, and patients with hands, arms and feet involvement and those with a negative family history of vitiligo.
Conclusion: The disease has a negative impact on the QoL in the majority of patients. The dermatologist should put an emphasis on the psychological problems of the disease among their patients during planning their future management course.
2. Hedayat K, Karbakhsh M, Ghiasi M, Goodarzi A, Fakour Y, Akbari Z, et al. Quality of life in patients with vitiligo: a cross-sectional study based on Vitiligo Quality of Life index (VitiQoL). Health Qual Life Outcomes. 2016; 14: 86. https://doi.org/10.1186/s12955-016-0490-y.19177700.
3. Silverberg NB. The epidemiology of vitiligo. Curr Derm Rep. 2015; 4: 36. https://doi.org/10.1007/s13671-014-0098-6.
4. Kota RS, Vora RV, Varma JR, Kota SK, Patel TM, Ganjiwale J.Study on Assessment of Quality of Life and Depression in Patients of Vitiligo. Indian Dermatol Online J. 2019; 10(2): 153-157.
5. Ongenae K, Van Geel N, De Schepper S, Naeyaert JM. Effect of vitiligo on self-reported health-related quality of life.Br J Dermatol. 2005; 152(6):1165-72.
6. Finlay AY, Khan GK. https://www.cardiff.ac.uk/medicine/resources/quality-of-life-questionnaires/ dermatology-life-quality-index.( date accessed 3, January, 2019)
7. Amer AA, Gao XH. Quality of life in patients with vitiligo: an analysis of the dermatology life quality index outcome over the past two decades. Int J Dermatol. 2016; 55(6): 608-14.
8. Al Robaee A A. Assessment of quality of life in Saudi patients with vitiligo in a medical school in Qassim province, Saudi Arabia. Saudi Med J. 2007; 28(9): 1414-7.
9. Dolatshahi M, Ghazi P, Feizy V, Hemami MR. Life quality assessment among patients with vitiligo: comparison of married and single patients in Iran. Indian J Dermatol Venereol Leprol. 2008; 74 (6): 700. [cited 2019 June 3]; 74:700. Available from: http://www.ijdvl.com/text.asp?2008/74/6/700/45141.
10. Mishra N, Rastogi MK, Gahalaut P, Agrawal S. Dermatology Specific Quality of Life in Vitiligo Patients and Its Relation with Various Variables: A Hospital Based Cross-sectional Study.J ClinDiagn Res. 2014; 8(6): YC01YC03. https://doi.org/10.7860/JCDR/2014/8248.4508.
11. Fitzpatrick TB. The Validity and Practicality of Sun-Reactive Skin Types I Through VI. Arch Dermatol. 1988; 124 (6):869–871.
12. Finlay AY and Khan GK. Dermatology Life Quality Index (DLQI): a simple practical measure for routine clinical use. Clin Exp Dermatol 1994; 19:210-216.
13. Pahwa P, Mehta M, Khaitan BK, Sharma VK, Ramam M. The psychosocial impact of vitiligo in Indian patients. Indian J Dermatol Venereol Lep rol. 2013; 79:679–85.
14. Belhadjali H, Amri M, Mecheri A, Doarika A, Khorchani H, Youssef M, et al. Vitiligo and quality of life: A case-control study. Ann Dermatol Venereol. 2007; 134:233–36.
15. CatucciBoza J, Giongo N, Machado P, Horn R, Fabbrin A, Cestari T. Quality of Life Impairment in Children and Adults with Vitiligo: A Cross-Sectional Study Based on Dermatology-Specific and Disease-Specific Quality of Life Instruments. Dermatology. 2016; 232(5): 619-625.
16. Mattoo SK, Handa S, Kaur I, Gupta N, Malhotra R. Psychiatric morbidity in vitiligo: Prevalence and correlates in India. J Eur Acad Dermatol Venereol. 2002; 16:573–78.
17. Basra MKA, Fenech R, Gatt RM, Salek MS, Finlay A.Y. The Dermatology Life Quality Index 1994-2007: A comprehensive review of validation data and clinical results. Br J Dermatol. 2008; 159: 997–1035.
18. Catucci Boza J, Giongo N, Machado P, Horn R, Fabbrin A, CestariT. Quality of Life Impairment in Children and Adults with Vitiligo: A Cross-Sectional Study Based on Dermatology-Specific and Disease-Specific Quality of Life Instruments. Dermatology. 2016; 232(5):619-625.
19. Basra MKA, Fenech R, Gatt RM, Salek MS, Finlay A.Y. The Dermatology Life Quality Index 1994-2007: A comprehensive review of validation data and clinical results. Br J Dermatol. 2008; 159:997–1035.
20. Bin Saif GA, Al-Balbeesi AO, Binshabaib R, Alsaad D, Kwatra SG, Alzolibani AA, et al. Quality of life in family members of vitiligo patients: a questionnaire study in Saudi Arabia. Am J Clin Dermatol. 2013 Dec; 14(6): 489-95