SURVIVAL RELATED FACTORS IN GASTRECTOMY SPECIMENS. A STUDY OF 65 CASES IN DUHOK CITY - IRAQ
Background: Gastric cancer is one of the commonest malignancies and one of the most common causes of cancer deaths worldwide. This study aims to investigate the survival-related factors in gastrectomy specimens.
Method: This is a cross-sectional retrospective study that included 65 gastrectomy specimens in Duhok City-Iraq over a period of 6 years from January 2014- November 2019.
The parameters sought included age, gender, histological type, grade, lymph node status, tumor size, resection margin status, and lymphovascular and perineural invasions. Patients were grouped for their ages with an interval of 10 years and pathological parameters were expressed in frequencies and percentages.
Results: The male to female ratio was 1.1:1, and the most affected age group was between 60-69 years. The intestinal type adenocarcinoma represented 64.61% of cases, and the remainders were of the diffuse type. The resection margins were tumor-free in 78.5% of cases, and 80% had a lymphovascular invasion. Perineural invasion was seen in 35.38% of the included patients. Only 16.92% of patients were negative for lymph node involvement, and the nodal status was N0: 16.9%, N1:58.5%, N2: 18.5%, and N3:6.1%, and 66.15% of them fell in T3 category. The majority of patients had more than 4 adverse survival-related factors.
Conclusion: The present study showed that most of gastric carcinoma patients had multiple bad prognostic factors a fact that mostly correlated to their late presentation and a finding that indicates the gloomy outcome for patients at least in the near foreseen future unless a screening program is rapidly initiated.
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